Interferential Stimulation
Description of Procedure or Service
Interferential current stimulation (IFS) is a type of electrical stimulation that uses paired electrodes of two independent circuits carrying high-frequency (4,000 Hz) and mediumfrequency (150 Hz) alternating currents. The superficial electrodes are aligned on the skin around the affected area. It is believed that IFS permeates the tissues more effectively and, with less unwanted stimulation of cutaneous nerves, is more comfortable than transcutaneous electrical nerve stimulation (TENS). Interferential stimulation has been investigated as a technique to reduce pain, improve function and range of motion (ROM), and treat a variety of gastrointestinal disorders. There are no standardized protocols for the use of interferential therapy; the therapy may vary according to the frequency of stimulation, the pulse duration, treatment time, and electrode-placement technique.
Regulatory Status:
A number of interferential stimulator devices have received 510(k) marketing clearance from the U.S. Food and Drug Administration (FDA), including the Medstar™ 100 (MedNet Services) and the RS-4i® (RS Medical). IFS may be included in multimodal electrotherapy devices such as transcutaneous electrical nerve stimulation and functional electrostimulation.
Related Policies
TENS (Transcutaneous Electrical Nerve Stimulation)
Percutaneous Electrical Nerve Stimulation (PENS) or Neuromodulation Therapy and Percutaneous Electrical Nerve Field Stimulation (PENFS)
***Note: This Medical Policy is complex and technical. For questions concerning the technical language and/or specific clinical indications for its use, please consult your physician.
Policy
Interferential Stimulation is considered investigational for all applications. BCBSNC does not cover investigational services or procedures.
Benefits Application
This medical policy relates only to the services or supplies described herein. Please refer to the Member's Benefit Booklet for availability of benefits. Member's benefits may vary according to benefit design; therefore member benefit language should be reviewed before applying the terms of this medical policy.
When Interferential Stimulation is covered
Not applicable
When Interferential Stimulation is not covered
Interferential current stimulation is considered investigational.
Policy Guidelines
For individuals who have musculoskeletal conditions who receive IFS, the evidence includes randomized controlled trials (RCTs) and meta-analyses. Relevant outcomes are symptoms, functional outcomes, quality of life, medication use, and treatment-related morbidity. Placebocontrolled RCTs have found that IFS when used to treat musculoskeletal pain and impaired function(s), does not significantly improve outcomes. Meta-analyses for IFS in musculoskeletal conditions have generally found IFS to be no more effective than other therapies. One network meta-analysis did find improvement with IFS compared with control, but the analysis is limited by indirect comparisons. The evidence is insufficient to determine that the technology results in an improvement in the net health outcome.
For individuals who have gastrointestinal disorders who receive IFS, the evidence includes RCTs. Relevant outcomes are symptoms, functional outcomes, quality of life, medication use and treatment-related morbidity. IFS has been tested for a variety of gastrointestinal conditions, with a small number of trials completed for each condition. Trials results are mixed, with some reporting benefit and others not. This body of evidence is inconclusive on whether IFS is an efficacious treatment for gastrointestinal conditions. The evidence is insufficient to determine that the technology results in an improvement in the net health outcome.
For individuals who have poststroke spasticity who receive IFS, the evidence includes RCTs. Relevant outcomes are symptoms, functional outcomes, quality of life, and treatment-related morbidity. The RCTs had small sample sizes and very short follow-up (immediately posttreatment to five weeks). The evidence is insufficient to determine that the technology results in an improvement in the net health outcome.
Billing/Coding/Physician Documentation Information
This policy may apply to the following codes. Inclusion of a code in this section does not guarantee that it will be reimbursed. For further information on reimbursement guidelines, please see Administrative Policies on the Blue Cross Blue Shield of North Carolina web site at www.bcbsnc.com. They are listed in the Category Search on the Medical Policy search page.
Applicable service codes: S8130, S8131
BCBSNC may request medical records for determination of medical necessity. When medical records are requested, letters of support and/or explanation are often useful, but are not sufficient documentation unless all specific information needed to make a medical necessity determination is included.
Scientific Background and Reference Sources
BCBSA Medical Policy Reference Manual, 1.01.24, 7/17/03
Specialty Matched Consultant Advisory Panel - 6/2004
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 12/14/2005
Specialty Matched Consultant Advisory Panel - 5/2006
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 12/12/2006
Specialty Matched Consultant Advisory Panel - 5/2008
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 10/6/2009
Specialty Matched Consultant Advisory Panel – 11/29/2010
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 11/11/2010
Specialty Matched Consultant Advisory Panel – 11/2011
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 12/8/2011
Specialty Matched Consultant Advisory Panel – 10/2012
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 12/13/2012
Specialty Matched Consultant Advisory Panel – 10/2013
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 12/12/2013
Specialty Matched Consultant Advisory Panel – 10/2014
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 12/11/2014
Specialty Matched Consultant Advisory Panel – 10/2015
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 6/16/2016
Specialty Matched Consultant Advisory Panel – 10/2016
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 9/14/2017
Specialty Matched Consultant Advisory Panel – 10/2017
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 6/14/2018
Specialty Matched Consultant Advisory Panel – 10/2018
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 6/13/2019
Specialty Matched Consultant Advisory Panel – 10/2019
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 6/18/2020
Specialty Matched Consultant Advisory Panel – 10/2020
BCBSA Medical Policy Reference Manual [Electronic Version], 1.01.24, 6/10/2021
Specialty Matched Consultant Advisory Panel – 10/2021
Hussein HM, Alshammari RS, Al-Barak SS, et al. A systematic review and meta-analysis investigating the pain-relieving effect of interferential current on musculoskeletal pain. Am J Phys Med Rehabil. Aug 31 2021. PMID 34469914
Specialty Matched Consultant Advisory Panel – 10/2022
Specialty Matched Consultant Advisory Panel – 10/2023
Medical Director Review- 10/2023
Specialty Matched Consultant Advisory Panel – 10/2024
Medical Director Review- 10/2024
Policy Implementation/Update Information
11/03 New policy.
4/8/04 Added, "Sequential stimulators that combine interferential current and muscle stimulation such as the RS-4i Sequential Stimulator are considered investigational. BCBSNC does not cover investigational services." to the noncovered section of the policy. Statement removed from Policy Guidelines.
7/29/04 Specialty Matched Consultant Advisory Panel review 6/22/04. No changes to criteria. Format changes for consistency. References added.
6/5/06 Specialty Matched Consultant Advisory Panel review
5/3/2006. No changes to policy statement. Rationale added to "Policy Guidelines" section. References added.
12/3/07 "Next Review Date" corrected. Policy number added to "Key Word" section.
6/30/08 Specialty Matched Consultant Advisory Panel review 5/29/08. No changes to policy statement. Policy status changed to Active policy, no longer scheduled for routine literature review. (btw)
6/22/10 Policy Number(s) removed (amw)
12/21/10 Removed from “Active policy, no longer scheduled for routine literature review.” To active policy. Policy “Description” revised. Policy statements reworded no change to policy intent. “Policy Guidelines” revised. References added. Specialty Matched Consultant Advisory Panel review 11/29/2010. References added. (btw)
1/1/12 Specialty Matched Consultant Advisory Panel review 11/30/11. “Description” revised. No change to policy intent. Rationale in “Policy Guidelines” updated. Added 2012 HCPCS codes S8130 and S8131 to the “Billing/Coding” section. (btw) 4/17/12 Reference added. (btw)
11/13/12 Specialty Matched Consultant Advisory Panel review 10/17/2012. Policy Guidelines updated. No change to policy intent. (btw)
2/12/13 Description and Policy Guidelines sections updated. No change to policy intent. Reference added. (btw)
11/12/13 Specialty Matched Consultant Advisory Panel review 10/16/2013. No change to policy. (btw)
2/25/14 Reference added. (btw)
11/25/14 Related Guideline added. Specialty Matched Consultant Advisory Panel review 10/28/2014. No change to Policy statement. (sk)
2/24/15 Reference added. (sk)
11/24/15 Specialty Matched Consultant Advisory Panel review 10/28/2015. (sk)
7/26/16 Reference added. Policy Guidelines updated. (sk)
11/22/16 Specialty Matched Consultant Advisory Panel review 10/26/2016. (sk)
11/10/17 Reference added. Specialty Matched Consultant Advisory Panel review 10/25/2017. (sk)
8/24/18 Reference added. (sk)
11/9/18 Specialty Matched Consultant Advisory Panel review 10/24/2018. (sk)
8/27/19 Reference added. (sk)
11/26/19 Specialty Matched Consultant Advisory Panel review 10/16/2019. (sk)
11/10/20 Reference added. Specialty Matched Consultant Advisory Panel review 10/21/2020. (sk)
8/10/21 Reference added. (sk)
11/16/21 Specialty Matched Consultant Advisory Panel review 10/20/2021. (sk)
5/2/23 Policy update. Reference added. Specialty Matched Consultant Advisory Panel review 10/19/2022. (sk)
11/7/23 Updated title of one Related Policy. References updated. Specialty Matched Consultant Advisory Panel review 10/2023. Medical Director review 10/2023. (ldh)
11/13/24 References updated. Specialty Matched Consultant Advisory Panel review 10/2024. Medical Director review 10/2024. (ldh)
Disclosures:
Medical policy is not an authorization, certification, explanation of benefits or a contract. Benefits and eligibility are determined before medical guidelines and payment guidelines are applied. Benefits are determined by the group contract and subscriber certificate that is in effect at the time services are rendered. This document is solely provided for informational purposes only and is based on research of current medical literature and review of common medical practices in the treatment and diagnosis of disease. Medical practices and knowledge are constantly changing and BCBSNC reserves the right to review and revise its medical policies periodically.
Blue Cross and Blue Shield of North Carolina does not discriminate on the basis of race, color, national origin, sex, age or disability in its health programs and activities. Learn more about our non-discrimination policy and no-cost services available to you.
Information in other languages: Español 中文 Tiếng Việt 한국어 Français العَرَبِيَّة Hmoob ру́сский Tagalog ગુજરાતી ភាសាខ្មែរ Deutsch हिन्दी ລາວ 日本語
© 2025 Blue Cross and Blue Shield of North Carolina. ®, SM Marks of the Blue Cross and Blue Shield Association, an association of independent Blue Cross and Blue Shield plans. All other marks and names are property of their respective owners. Blue Cross and Blue Shield of North Carolina is an independent licensee of the Blue Cross and Blue Shield Association.